Genzyme Provides Update on Product Supply and Consent Decree Terms

CAMBRIDGE, Mass. - Genzyme Corp.

April 21, 2010 - Cerezyme® Genzyme achieved its goal of building a small inventory buffer during the first quarter. The current shipping allocation of 50 percent of demand will be extended, however, due to an interruption in operations at the company's Allston facility late in the quarter. The interruption resulted from an unexpected city electrical power failure that compounded issues with the plant's water system, which have been corrected. The facility is fully operational. Genzyme estimates that it will need to continue the 50 percent shipping allocation for 2-3 months. The company will provide a more precise supply update within a month, after determining whether Cerezyme® material that was unfinished when the interruption occurred can be finished, the impact of the pending consent decree on product release timelines and a more accurate assessment of global demand. Genzyme achieved its goal of building a small inventory buffer during the first quarter.

The current shipping allocation of 50 percent of demand will be extended, however, due to an interruption in operations at the company's Allston facility late in the quarter. The interruption resulted from an unexpected city electrical power failure that compounded issues with the plant's water system, which have been corrected. The facility is fully operational. Genzyme estimates that it will need to continue the 50 percent shipping allocation for 2-3 months. The company will provide a more precise supply update within a month, after determining whether Cerezyme® material that was unfinished when the interruption occurred can be finished, the impact of the pending consent decree on product release timelines and a more accurate assessment of global demand.

The entire release can be viewed at http://www.gaucherdisease.org/news.php